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SYLLABUS

Unit-I

Flow of Fluids Types of manometers, Reynold’s number and its significance, Bernoulli’s theorem and its applications. Energy losses, orifice meter, venturimeter, pitot tube and rotometer. Size Reduction Objectives, mechanisms & laws governing size reduction, factors affecting size reduction, principles, construction, working, uses, merits and demerits of hammer mill, ball mill, fluid energy mill, edge runner mill & end runner mill. Size Separation Objectives, applications & mechanisms of size separation. Official standards of powders, sieves. Size separation-principles, construction, working, uses, merits and demerits of sieve shaker, cyclone separator, air separator, bag filter & elutriation tank.

Unit-II

Heat Transfer Objectives, applications & heat transfer mechanisms. Fourier’s law, heat transfer by conduction, convection & radiation. Heat interchangers & heat exchangers. Evaporation Objectives, applications and factors influencing evaporation, differences between evaporation and other heat process. Principles, construction, working, uses, merits and demerits of steam jacketed kettle, horizontal tube evaporator, climbing film evaporator, forced circulation evaporator, multiple effect evaporator & economy of multiple effect evaporator. Distillation Basic principles and methodology of simple distillation, flash distillation, fractional distillation, distillation under reduced pressure, steam distillation & molecular distillation

Unit-III

Drying Objectives, applications & mechanisms of drying process. Measurements & applications of equilibrium moisture content, rate of drying curve. Principles, construction, working, uses, merits and demerits of tray dryer, drum dryer, spray dryer, fluidized bed dryer, vacuum dryer, freeze dryer. Mixing Objectives, applications & factors affecting mixing, Difference between solid and liquid mixing, mechanism of solid mixing, liquids mixing and semisolids mixing. Principles, construction, working, uses, merits and demerits of double cone blender, twin-shell blender, ribbon blender, sigma blade mixer, planetary mixers, propellers, turbines, paddles & silverson emulsifier.

Unit-IV

Filtration Objectives, applications, theories & factors influencing filtration, filter aids, filter medias. Principle, construction, working, uses, merits and demerits of plate & frame filter, filter leaf, rotary drum filter, meta filter & cartridge filter, membrane filters and seitz filter. Centrifugation Objectives, principle & applications of centrifugation. Principles, construction, working, uses, merits and demerits of Perforated basket centrifuge, non-perforated basket centrifuge, semi continuous centrifuge & super centrifuge.

Unit-V

Materials of Pharmaceutical Plant Construction, Corrosion and its Prevention Factors affecting during materials selected for Pharmaceutical plant construction. Theories of corrosion, types of corrosion and their prevention. Ferrous and nonferrous metals, inorganic and organic non metals, basic of material handling systems.