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SYLLABUS

Unit-I

1. Pharmacology of Drugs Acting on Cardiovascular System (a) Introduction to haemodynamics and electrophysiology of heart (b) Drugs used in congestive heart failure (c) Antihypertensive drugs (d) Antianginal drugs (e) Antiarrhythmic drugs (f) Antihyperlipidaemic drugs

Unit-II

1. Pharmacology of Drugs Acting on Cardiovascular System (a) Drug used in the therapy of shock (b) Haematinics, coagulants and anticoagulants (c) Fibrinolytics and antiplatelet drugs (d) Plasma volume expanders. 2. Pharmacology of Drugs Acting on Urinary System (a) Diuretics (b) Antidiuretics.

Unit-III

3. Autacoids and Related Drugs (a) Introduction to autacoids and classification (b) Histamine, 5-HT and their antagonists (c) Prostaglandins, thromboxanes and leukotrienes (d) Angiotensin, bradykinin and substance P (e) Non-steroidal anti-inflammatory agents (f) Antigout drugs (g) Antirrheumatic drugs.

Unit-IV

4. Pharmacology of Drugs Acting on Endocrine System (a) Basic concepts in endocrine pharmacology (b) Anterior pituitary hormones- analogues and their inhibitors (c) Thyroid hormones- analogues and their inhibitors (d) Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D (e) Insulin, oral hypoglycemic agents and glucagon (f) ACTH and corticosteroids.

Unit-V

5. Pharmacology of Drugs Acting on Endocrine System (a) Androgens and Anabolic steroids (b) Estrogens, progesterone and oral contraceptives (c) Drugs acting on the uterus. 6. Bioassay (a) Principles and applications of bioassay (b) Types of bioassay (c) Bioassay of insulin, oxytocin, vasopressin, ACTH, d-tubocurarine, digitalis, histamine and 5-HT.