Verify Account

SYLLABUS

Unit-I

Tablets: Introduction to different types of tablets, granulation technology on large-scale by various techniques, types of tablet compression machinery and the equipments employed, evaluation of tablets.

Unit-II

Coating of Tablets: Types of coating, coating materials and their selection, formulation of coating solution, equipments for coating, coating processes and evaluation of coated tablets.

Unit-III

Capsules: Advantages and disadvantages of capsule dosage forms, material for production of hard and soft gelatin capsules, sizes of capsules, capsule filling, processing problems in capsule manufacturing, importance of base absorption and minimum/gm factor in soft capsules, quality control, stability testing and storage of capsule dosage forms.

Unit-IV

Microencapsulation: Types and importance in pharmacy, microencapsulation by coacervation phase separation, multiorifice centrifugal separation, spray drying, spray congealing, polymerization complex emulsion, air suspension technique, pan coating techniques and evaluation of microcapsules.

Unit-V

Parenteral Products (a) Preformulation factors, routes of administration, water for injection, treatment, apyrogenicity, nonaqueous vehicles, isotonicity and methods of its adjustment. (b) Formulation details, containers and closures and their selection. (c) Prefilling treatment, washing and sterilization of containers and closures, preparation of solutions and suspensions, filling and closing of ampoules, vials, infusion fluids, lyophilization and preparation of sterile powders, equipment for large-scale manufacture and evaluation of parenteral products.

Unit-VI

Aseptic techniques, sources of contamination and methods of prevention. Design of aseptic area, laminar flow benches, services and maintenance.

Unit-VII

Packaging of Pharmaceutical Products: Packaging components, types, specifications and methods of evaluation as per IP. Factors influencing choice of containers, package testing, legal and other official requirements for containers.

Unit-VIII

Methods of packing of solid, liquid and semisolid dosage forms, factors influencing packing material and stability aspects of packaging.